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Transdermal Patch Holder with 80mm (3.15") opening and 16 Mesh screen.
Use in Paddle Over Disk Applications
Method
Transdermal or patch testing is carried out using USP method 5 (paddle over disc) or USP method 6, the rotating cylinder.
With paddle over disc, the transdermal patch is placed between a glass disc and an inert PTFE mesh. This is placed at the bottom of the vessel, with the mesh facing upwards, under a rotating paddle.
Unlike dissolution testing, transdermal testing is carried out at 32°C to reflect the lower temperature of the skin. Other variables such as the height setting and sampling requirements are the same as dissolution testing.
